Moving from nature to nurture: a systematic review and meta-analysis of environmental factors associated with juvenile idiopathic arthritis.
Sarah L N ClarkeKatie S MageeanIlaria MaccoraSean HarrisonGabriele SimoniniGemma C SharpCaroline L ReltonAthimalaipet V RamananPublished in: Rheumatology (Oxford, England) (2021)
This review identifies several environmental factors associated with JIA and demonstrates the huge breadth of environmental research undertaken over five decades. We also highlight the challenges of combining data collected over this period due to limited between study comparability, evolution in healthcare and social practices, and changing environment, which warrant consideration when planning future studies.