Enterococcus faecium strain R30 increases red blood cell velocity and prevents capillary regression in the soleus of hindlimb-unloaded rats via the eNOS/VEGF pathway.

Yusuke HirayamaRyosuke NakanishiAiro TategakiNoriaki MaeshigeHiroyo KondoAkihiko IshiharaRoland R RoyHidemi Fujino

Published in: Microcirculation (New York, N.Y. : 1994) (2018)

The results suggest that R30 increases VRBC in the soleus muscle via muscle sympathetic nerve activity (Experiment 1) and that R30 supplementation lessens the capillary regression normally associated with HU via the eNOS/VEGF pathway (Experiment 2).

Keyphrases

endothelial cells
red blood cell
vascular endothelial growth factor
skeletal muscle
nitric oxide synthase
pi k akt
mouse model
blood flow
biofilm formation