Insulin signaling pathway assessment by enhancing antioxidant activity due to morin using in vitro rat skeletal muscle L6 myotubes cells.
Praveen Kumar IssacRupmanjari KaranAjay GuruR PachaiappanMariadhas Valan ArasuNaif Abdullah Al-DhabiKi Choon ChoiRamasamy HarikrishnanJesu Arockia RajPublished in: Molecular biology reports (2021)
Morin has the ability to act as an anti-oxidant by lowering ROS levels and demonstrating insulin mimetic activity by reversing insulin resistance associated with oxidative stress.
Keyphrases
- induced apoptosis
- insulin resistance
- oxidative stress
- type diabetes
- skeletal muscle
- signaling pathway
- glycemic control
- dna damage
- endoplasmic reticulum stress
- cell cycle arrest
- metabolic syndrome
- pi k akt
- high fat diet
- adipose tissue
- cell death
- diabetic rats
- ischemia reperfusion injury
- polycystic ovary syndrome
- high fat diet induced
- reactive oxygen species
- epithelial mesenchymal transition
- anti inflammatory
- cell proliferation
- heat shock protein
- heat shock