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Necrotic enteritis in chickens: a review of pathogenesis, immune responses and prevention, focusing on probiotics and vaccination.

Mohammadali AlizadehBahram ShojadoostNitish BoodhooJake AstillKhaled Taha-AbdelazizDouglas C HodginsRaveendra R KulkarniShayan Sharif
Published in: Animal health research reviews (2022)
Necrotic enteritis (NE), caused by Clostridium perfringens (CP), is one of the most common of poultry diseases, causing huge economic losses to the poultry industry. This review provides an overview of the pathogenesis of NE in chickens and of the interaction of CP with the host immune system. The roles of management, nutrition, probiotics, and vaccination in reducing the incidence and severity of NE in poultry flocks are also discussed.
Keyphrases
  • immune response
  • antimicrobial resistance
  • heat stress
  • risk factors
  • physical activity
  • disease virus
  • toll like receptor
  • inflammatory response