Birth Defect Co-Occurrence Patterns Among Infants With Cleft Lip and/or Palate.
Maria Luisa Navarro SanchezRenata H BenjaminLaura E MitchellPeter H LangloisMark A CanfieldMichael D SwartzAngela E ScheuerleDaryl A ScottHope NorthrupChristian P SchaafJoseph W RayScott D McLeanHan ChenPhilip J LupoA J AgopianPublished in: The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association (2021)
The patterns of defects we observed co-occurring with clefts more often than expected may help improve our understanding of the relationships between multiple defects. Further work to better understand some of the top defect combinations could reveal new phenotypic subgroups and increase our knowledge of the developmental mechanisms that underlie the respective defects.
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