Periodic Limb Movements while Awake ( PLMA ) as a Manifestation of Wearing-Off in Parkinson's Disease: A Case Series and Review of the Literature.

Sohaila Alshimemeri Daniel Garbin Di Luca Diana Angelika Olszewska Eoin Mulroy Kailash P BhatiaSusan H FoxAnthony E Lang

Published in: Movement disorders clinical practice (2022)

We describe, for the first time to our knowledge, PLMA as a wearing-off phenomenon in PD. This entity could be classified in the spectrum of "low-dose dyskinesia," as we found that it was highly responsive to dopaminergic treatment.

Keyphrases

low dose
healthcare
high dose
combination therapy
drug delivery