Amphiregulin deletion strongly attenuates the development of estrogen receptor-positive tumors in p53 mutant mice.
David R MeierMegan A GirtmanKristopher A LofgrenParaic A KennyPublished in: Breast cancer research and treatment (2019)
This study underlines the importance of the EGFR ligand, Amphiregulin, as a key mediator of estrogen receptor action in breast cancer.