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Amphiregulin deletion strongly attenuates the development of estrogen receptor-positive tumors in p53 mutant mice.

David R MeierMegan A GirtmanKristopher A LofgrenParaic A Kenny
Published in: Breast cancer research and treatment (2019)
This study underlines the importance of the EGFR ligand, Amphiregulin, as a key mediator of estrogen receptor action in breast cancer.
Keyphrases
  • estrogen receptor
  • small cell lung cancer
  • epidermal growth factor receptor
  • wild type
  • tyrosine kinase
  • high fat diet induced
  • adipose tissue
  • young adults