Modeling strategies to improve parameter estimates in prognostic factors analyses with patient-reported outcomes in oncology.
Francesco CottoneNina DeliuGary S CollinsAmelie AnotaFranck BonnetainKristel Van SteenDavid CellaFabio EfficacePublished in: Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation (2019)
Our findings suggest that the Cox-R is the best approach when performing prognostic factor analyses with multiple and collinear PRO scales, particularly in situations of high multicollinearity, small sample sizes and low event rates.