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Transcriptomic Profiling of Lactotroph Pituitary Neuroendocrine Tumors via RNA Sequencing and Ingenuity Pathway Analysis.

Yujiro HattoriShigeyuki TaharaHitoshi OzawaAkio MoritaHirotaka Ishii
Published in: Neuroendocrinology (2024)
This study provides a comprehensive transcriptomic profile of lactotroph PitNETs and highlights the potential involvement of lincRNAs and specific signaling pathways in tumor pathogenesis. The identified upstream regulators may be potential therapeutic targets for future investigations.
Keyphrases
  • single cell
  • neuroendocrine tumors
  • rna seq
  • signaling pathway
  • human health
  • transcription factor
  • cell proliferation
  • endoplasmic reticulum stress