Desmopressin in haemophilia: The need for a standardised clinical response and individualised test regimen.
Sara C M StoofL M SchütteF W G LeebeekM H CnossenM J H A KruipPublished in: Haemophilia : the official journal of the World Federation of Hemophilia (2017)
We suggest standardised desmopressin response based on clinically relevant FVIII:C levels, e.g. 0.30 and 0.50 IU/mL. In addition, patients with <0.30 IU/mL FVIII:C after 1 hour (non-responder) or ≥0.80 IU/mL (sustained responder) do not require subsequent blood sampling. However, patients with ≥0.30-0.79 IU/mL FVIII:C after 1 hour should undergo blood sampling after 6 hours to additionally determine response sustainability.
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