IL-6-PAD4 axis in the earliest phase of arthritis in knock-in gp130F759 mice, a model for rheumatoid arthritis.

Ayano YahagiTaro SaikaHiroyasu HiranoMiwa Takai-ImamuraFumio TsujiHiroyuki AonoMasanori IsekiYoshitaka MoritaHideya IgarashiYukihiko SaekiKatsuhiko Ishihara

Published in: RMD open (2019)

The IL-6-PAD4 axis operates in the earliest phase of arthritis in gp130F759, implicating it in early RA.

Keyphrases

rheumatoid arthritis
disease activity
interstitial lung disease
ankylosing spondylitis
type diabetes
systemic sclerosis
systemic lupus erythematosus
metabolic syndrome
skeletal muscle
insulin resistance
wild type