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Hematologic safety of palbociclib in combination with endocrine therapy in patients with benign ethnic neutropenia and advanced breast cancer.

Filipa C LynceMatthew J BlackburnRebecca ZhuoChristopher GallagherOlwen M HahnMaysa Abu-KhalafMahsa MohebtashTianmin WuPaula R PohlmannAsma DilawariShruti R TiwariAmi ChitaliaRobert WarrenMing TanAyesha N Shajahan-HaqClaudine Isaacs
Published in: Cancer (2021)
These findings suggest that palbociclib is well tolerated in African American women with HR-positive/HER2-negative ABC. Duffy null status may affect the incidence of grade 3 neutropenia, dose intensity, and possibly clinical benefit.
Keyphrases
  • african american
  • metastatic breast cancer
  • chemotherapy induced
  • risk factors
  • high intensity
  • young adults
  • smoking cessation