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A Systematic Review of Nonautologous Graft Materials Used in Human Tympanoplasty.

Iman GhanadMarc D PolanikDanielle R TrakimasRenata M KnollMelissa Castillo-BustamanteNicole L BlackElliott Davin KozinAaron Kyle Remenschneider
Published in: The Laryngoscope (2020)
The majority of publications reviewing nonautologous materials in tympanoplasty evaluate acute or traumatic perforations, and few rigorously report hearing outcomes. Given available data, porcine submucosa and basic fibroblast growth factor may hold promise for chronic perforation closure. Future studies should report closure rates and hearing outcomes in perforations >8 weeks duration. Laryngoscope, 131:392-400, 2021.
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