Hydrogen sulfide downregulates colonic afferent sensitivity by a nitric oxide synthase-dependent mechanism in mice.
Xiaomeng XuShuang LiYao ShiYan TangWen LuTing HanBing XueJing Xin LiChuanyong LiuPublished in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2018)
H2 S downregulates colonic mesenteric afferent sensitivity by a nNOS-dependent mechanism in mice. Our findings may demonstrate a new mechanism for the antinociceptive effect of H2 S in colon.