Examination and prognostic implications of the unique microenvironment of breast cancer brain metastases.

Maria J SambadeGrace PrinceAllison M DealDimitri TrembathMegan McKeeAmy GarrettKevin KeithJuanita RamirezBentley MidkiffKimberly BlackwellSarah SammonsJose Pablo LeoneAdam BrufskyAki MorikawaEdi BrogiAndrew SeidmanMatthew EwendLisa A CareyStergios J MoschosRonald L HamiltonBenjamin VincentCarey K Anders

Published in: Breast cancer research and treatment (2019)

Gliosis confers superior prognosis in TNBC BM; immune infiltrate and hemorrhage correlate with superior prognosis in HER2+ BCBM. Understanding the metastatic microenvironment of BCBM refines prognostic considerations and may unveil novel therapeutic strategies.

Keyphrases

brain metastases
small cell lung cancer
stem cells
squamous cell carcinoma
young adults