Inhibiting IGF1R-mediated Survival Signaling in Head and Neck Cancer with the Peptidomimetic SSTN IGF1R .

Noah A Stueven DeannaLee M Beauvais Rong Hu Randall J Kimple Alan C Rapraeger

Published in: Cancer research communications (2023)

. A corresponding blockade in PDX growth in the presence of this inhibitor demonstrates that therapies designed to target this mechanism will likely offer promising outcomes for patients with head and neck cancer.

Keyphrases

pi k akt
binding protein
signaling pathway
growth hormone
free survival
skeletal muscle
cell proliferation