Identifying Parkinson's disease and parkinsonism cases using routinely collected healthcare data: A systematic review.
Zoe HardingTim WilkinsonAnna J StevensonSophie HorrocksAmanda LyChristian SchnierDavid P BreenKristiina RannikmäeCathie L M SudlowPublished in: PloS one (2019)
In many settings, routinely collected datasets generate good PPVs and reasonable sensitivities for identifying PD and parkinsonism cases. However, given the wide range of identified accuracy estimates, we recommend cohorts conduct their own context-specific validation studies if existing evidence is lacking. Further research is warranted to investigate primary care and medication datasets, and to develop algorithms that balance a high PPV with acceptable sensitivity.