A Constitutional Activating MET Mutation Makes the Genetic Link between Malignancies and Chronic Inflammatory Diseases.

Morad El BouchtaouiMarcio Do CruzeiroChristophe LeboeufIrmine Loisel-FerreiraCarèle FedronieChrystophe FerreiraRachida Ait El FarMarianne ZiolMarc EspiéGéraldine FalgaroneBruno CassinatJean-Jacques KiladjianJean-Paul FeugeasAnne JaninGuilhem Bousquet

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2019)

Our study opens a considerable field of application in the domain of constitutional genetics, to establish genetic links between cancers and other very different severe diseases.

Keyphrases

genome wide
copy number
signaling pathway
early onset
young adults