The role of the left atrial function in the surgical management of aortic and mitral valve disease.
Matteo CameliCarlotta SciaccalugaGiulia Elena MandoliFlavio D'AscenziCharilaos TsioulpasSergio MondilloPublished in: Echocardiography (Mount Kisco, N.Y.) (2019)
The right management of both mitral and aortic disease can be challenging, especially in asymptomatic patients. The current guidelines recommend valve repair or replacement when symptoms arise or when there is an evident left ventricular dysfunction. However, deciding the optimal surgical timing can be very difficult, since the line between the absence of symptoms and being minimally symptomatic, especially in the elderly, is blurred. Another relevant issue regards the second surgical criterion: operating on a patient with a reduced left ventricular ejection fraction or with a dilated left ventricle might jeopardize the possibility of a fully reverse remodeling of the heart after surgery. In this scenario, the left atrium might play an important role. In particular, left atrial deformation might be a very useful tool to detect early ultrastructural alterations, and help or support guiding a patient-tailored treatment at an early stage, optimizing the outcome in the long term.
Keyphrases
- newly diagnosed
- left atrial
- mitral valve
- left ventricular
- aortic stenosis
- ejection fraction
- heart failure
- early stage
- hypertrophic cardiomyopathy
- cardiac resynchronization therapy
- acute myocardial infarction
- pulmonary artery
- aortic valve
- case report
- atrial fibrillation
- clinical practice
- squamous cell carcinoma
- smoking cessation
- end stage renal disease
- chronic kidney disease
- peritoneal dialysis
- combination therapy
- aortic dissection
- prognostic factors
- coronary artery disease
- patient reported outcomes
- acute coronary syndrome
- neoadjuvant chemotherapy
- radiation therapy