Login / Signup

Antifeedant effect of polygodial and drimenol derivatives against Spodoptera frugiperda and Epilachna paenulata and quantitative structure-activity analysis.

Iván J MontenegroSoledad Del CorralGeorgina N Diaz NapalMaría C CarpinellaMarco MelladoAlejandro M MadridJoan VillenaSara M PalaciosMauricio A Cuellar
Published in: Pest management science (2018)
The results suggest that drimanic compounds have potential as new agents against S. frugiperda and E. paenulata. A quantitative structure-activity relationship (QSAR) analysis of the whole series, supported by electronic studies, suggested that drimanic compounds have structural features necessary for increasing antifeedant activity, namely a C-9 carbonyl group and an epoxide at C-8 and C-9. © 2018 Society of Chemical Industry.
Keyphrases
  • structure activity relationship
  • high resolution
  • molecular docking
  • molecular dynamics
  • human health