Development of Ultraviolet-Shielding Bamboo/Silk Fibroin Hybrid Films with Good Mechanical Properties: A Proof Study on Human Keratinocyte Cells.
Silvia Bittolo BonValeria LiberaMaria Rachele CeccariniRocco MalaspinaMichela CodiniLuca ValentiniPublished in: Polymers (2024)
In this study, we report the preparation and characterization of water-stable films with UV-shielding and good mechanical properties, exploiting the synergistic effect of regenerated silk fibroin and bamboo-derived cellulose. Silk fibroin (SF)/bamboo (B) hybrid films are achieved by solubilizing both silk and bamboo fibers in formic acid with added CaCl 2 . Infrared spectroscopy indicates that SF, when combined with bamboo, undergoes a conformational transition, providing evidence of an increase in SF crystallinity. Exploiting the intrinsic absorption of SF in the ultraviolet region, UV-Vis spectroscopy was used to assess the glass transition temperature (T g ) of SF/B films, showing a decrease in T g by increasing the SF content. The addition of 10 wt% SF to the B matrix improved the elastic modulus by about 10% while conserving the strain at break with respect to the neat B films, increasing the UV shielding properties, while water absorption suggested the material's hydrophilic and swelling capacity even after one month. The hybrid films showed, under solar irradiation, a photoprotective behavior on keratinocyte human cells by increasing cellular viability. These findings may find potential applications in functional fabrics.
Keyphrases
- tissue engineering
- room temperature
- carbon nanotubes
- wound healing
- endothelial cells
- single molecule
- ionic liquid
- high resolution
- molecular dynamics
- risk assessment
- drug delivery
- neoadjuvant chemotherapy
- cell proliferation
- mass spectrometry
- locally advanced
- liquid chromatography
- rectal cancer
- solid phase extraction
- solid state