Pyruvate kinase deficiency in children.

Satheesh ChonatStefan W EberSusanne HolzhauerNina KollmarD Holmes MortonBertil GladerEllis J NeufeldHassan M YaishJennifer A RothmanMukta SharmaYaddanapudi RavindranathHeng WangVicky R BreakeySujit ShethHeather A BradeenHasan Al-SayeghWendy B LondonRachael F Grace

Published in: Pediatric blood & cancer (2021)

There is a high burden of disease in children with PKD, with wide practice variation in monitoring and treatment. Clinicians must recognize the spectrum of the manifestations of PKD for early diagnostic testing, close monitoring, and management to avoid serious complications in childhood.

Keyphrases

young adults
healthcare
polycystic kidney disease
palliative care
risk factors
tyrosine kinase
childhood cancer