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Evaluation of recombinant baculovirus clearance during rAAV production in Sf9 cells using a newly developed fluorescent-TCID 50 assay.

Ningguang LuoXiangqun ChenJinzhong LiDerrick HuynhYing LiLi OuShengjiang Liu
Published in: Frontiers in medicine (2024)
assay to detect rBV infectivity, which can be widely applied in AAV manufacturing using the baculovirus system.
Keyphrases
  • high throughput
  • induced apoptosis
  • cell cycle arrest
  • quantum dots
  • endoplasmic reticulum stress
  • living cells
  • gene therapy
  • single cell