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Tumor-targeted nanoflowers regulate glutamine metabolism and amplify oxidative stress for synergistic therapy.

Mengzhen WangKaixian WangXiaohan LiuMingwan ShiHuiwen ZhangXia ZhangRuyue WeiNa LiWei PanBo Tang
Published in: Chemical communications (Cambridge, England) (2023)
We designed and synthesized tumor-targeted nanoflowers to inhibit glutamine metabolism and amplify oxidative stress, which could synergistically suppress tumor growth.
Keyphrases
  • oxidative stress
  • cancer therapy
  • dna damage
  • ischemia reperfusion injury
  • diabetic rats
  • induced apoptosis
  • drug delivery
  • mesenchymal stem cells
  • endoplasmic reticulum stress
  • heat stress