Outcomes following grade V subarachnoid haemorrhage: A single-centre retrospective study.
Minny OjhaMark E FinnisMichael HeckelmannEamon Patrick RaithStewart MoodieMarianne J ChapmanBenjamin Aj ReddiMatthew J MaidenPublished in: Anaesthesia and intensive care (2020)
SummaryGrade V subarachnoid haemorrhage is associated with high mortality and morbidity, yet there are few contemporary reports on the treatment provided and outcomes of these patients. In this single-centre retrospective cohort study, we primarily sought to determine the 12-month mortality of patients admitted to the Royal Adelaide Hospital intensive care unit between 2006 and 2016 with grade V subarachnoid haemorrhage. Secondary objectives were to describe treatments provided, patient destination following hospital discharge, organ donation and hospital financial costs. Over the 11-year study period, there were 139 patients admitted with grade V subarachnoid haemorrhage. The annual number of admissions did not change over time. The median age was 56 (interquartile range 48-70) years, 88 (63%) were female and 77 (55%) had a procedure to isolate an aneurysm. There were 77 (55%) patients who died in the intensive care unit, 87 (63%) died in hospital and 89 (64%) had died at 12 months. Of the 52 patients who survived to hospital discharge, 33 (63%) were transferred to a rehabilitation facility, 17 (33%) to another acute care hospital and two (4%) were discharged. Of the 87 patients who died in hospital, 45 (52%) donated organs. The total hospital cost of managing this cohort was A$8.3 million, with a median cost of A$41,824 (interquartile range A$9,933-A$97,332) per patient. Grade V subarachnoid haemorrhage has a high mortality rate, with one-third of patients alive after one year.
Keyphrases
- acute care
- end stage renal disease
- intensive care unit
- healthcare
- adverse drug
- ejection fraction
- chronic kidney disease
- newly diagnosed
- peritoneal dialysis
- cardiovascular events
- prognostic factors
- coronary artery
- risk factors
- type diabetes
- metabolic syndrome
- emergency department
- coronary artery disease
- adipose tissue
- young adults
- insulin resistance
- combination therapy
- replacement therapy