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Brain microenvironment-driven resistance to immune and targeted therapies in acral melanoma.

Rebecca Jane LeeGarima KhandelwalFranziska BaenkeAlessio CannistraciKenneth MacleodPiyushkumar MundraGarry AshtonAmit MandalAmaya VirosGabriela GremelElena GalvaniMatthew SmithNeil CarragherNathalie DhomenCrispin MillerPaul LoriganRichard Marais
Published in: ESMO open (2021)
Heterogeneous tumour interactions within the brain microenvironment enable progression on immune and targeted therapies and should be targeted in salvage treatments.
Keyphrases
  • resting state
  • white matter
  • stem cells
  • functional connectivity
  • cerebral ischemia
  • multiple sclerosis