Two new constituents from the aerial parts of Salvia miltiorrhiza Bge.

Two new constituents: a neolignan, salignan A ( 1 ) and a phenolic acid, salside A ( 2 ), along with two known compounds ( 3 , 4 ) have been isolated from the aerial parts of Salvia miltiorrhiza Bge. All structures were assigned on the basis of detailed spectroscopic analyses. The absolute configuration of 1 was characterised by electronic circular dichroism (ECD) spectroscopy. Compounds 1 and 3 exhibited moderate inhibitory effects on nitric oxide (NO) production in LPS-induced RAW264.7 cells, and the IC 50 values are 11.58 and 10.73 μM, respectively. Compound 4 displayed moderate antioxidant activity to scavenge DPPH and ABTS radicals, and the IC 50 values are 7.96 and 1.10 μM, respectively.