Use of methylphenidate and reporting of valvular heart disease: Global pharmacovigilance analysis in children and adults.

Estelle Ayme-Dietrich Florentia Kaguelidou Gilles Bertschy Laurent Chouchana

Published in: Pharmacoepidemiology and drug safety (2024)

VHD reporting appears rare with MPH compared to other adverse events and is increased in adults only. Our findings support a potential safety signal of VHD in adults exposed to MPH. A risk in that population cannot be excluded and requires further assessment.

Keyphrases

adverse drug
attention deficit hyperactivity disorder
young adults
atrial fibrillation
emergency department
aortic valve
climate change
autism spectrum disorder