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Potential effects of angiogenesis-related factors on the severity of APAC and surgical outcomes of trabeculectomy.

Jing WangMing-Shui FuMin-Wen ZhouBi-Lian KeZhi-Hua ZhangXun Xu
Published in: BMC ophthalmology (2021)
The levels of EPO, PDGF-CC and -DD were significantly elevated in failure group. EPO level correlated with preoperative IOP and numbers of eyedrops, and higher EPO level in aqueous humor is a risk factor for trabeculectomy failure. It can be a biomarker to estimate the severity of APAC and the success rate of surgery. The investigation of mechanism of EPO in APAC a may have potential clinical applications for the surgical treatment of APAC.
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