Validity of the NIH toolbox cognitive battery in a healthy oldest-old 85+ sample.

Sara A NolinHannah CowartStacy MerrittKatalina McInerneyP K BharadwajMary Kate FranchettiDavid A RaichlenCortney J JessupG Alex HishawEmily J Van EttenTheodore P TrouardDavid S GeldmacherVirginia G WadleyEric S PorgesAdam J WoodsRon A CohenBonnie E LevinTatjana RundekGene E AlexanderKristina M Visscher

Published in: Journal of the International Neuropsychological Society : JINS (2022)

The NIH TB-CB is a valid assessment for the oldest-old samples, with relatively weak validity in the domain of executive functioning. Computer use's impact on composite scores could be due to the executive demands of learning to use a tablet. Strong relationships of executive function with other cognitive domains could be due to cognitive dedifferentiation. Overall, the NIH TB-CB could be useful for testing cognition in the oldest-old and the impact of aging on cognition in older populations.

Keyphrases

mycobacterium tuberculosis
working memory
mild cognitive impairment
white matter
physical activity
machine learning
community dwelling
multiple sclerosis
middle aged
genetic diversity
solid state