Association of dipeptidyl peptidase-4 inhibitor initiation at glycated haemoglobin <7.5% with reduced major clinical events mediated by low glycated haemoglobin variability.
Johnny T K CheungAimin YangHongjiang WuEric S H LauJuliana Nga Man LuiAlice Pik-Shan KongRonald Ching-Wan MaAndrea On Yan LukElaine Y K ChowJuliana Chung Ngor ChanPublished in: Diabetes, obesity & metabolism (2024)
In Chinese patients with T2D, avoiding therapeutic inertia with intensified glycaemic control at HbA1c <7.5% using drugs with low risk of hypoglycaemia and good tolerability, such as DPP4i, delayed insulin treatment, reduced HbA1c variability and improved clinical events.