Alpha-Mangosteen lessens high-fat/high-glucose diet and low-dose streptozotocin induced-hepatic manifestations in the insulin resistance rat model.

Vivian SoetiknoPrisma AndiniMiskiyah IskandarClark Christensen MatheosJoshua Alward HerdimanIqbal Kevin KyleMuhammad Nur Imaduddin SumaMelva LouisaAri Estuningtyas

Published in: Pharmaceutical biology (2023)

the modulation of the AMPK/SREBP-1c/ACC pathway and it could be a potential drug candidate to prevent IR-induced hepatic manifestations.

Keyphrases

high glucose
endothelial cells
diabetic rats
low dose
insulin resistance
high fat diet
oxidative stress
metabolic syndrome
skeletal muscle
type diabetes
physical activity
adipose tissue
emergency department
weight loss
polycystic ovary syndrome
human health
protein kinase
stress induced