Digital droplet PCR-based chimerism analysis for monitoring of hematopoietic engraftment after allogeneic stem cell transplantation.

Thomas MikaAlexander BaraniskinSwedlana LadiganGerald WulfSascha DierksDetlef HaaseKarin SchorkMichael TurewiczMartin EisenacherWolff SchmiegelRoland SchroersSusanne Klein-Scory

Published in: International journal of laboratory hematology (2019)

According to our data, chimerism analysis by ddPCR has an excellent correlation with STR-based analyses. Due to its fast and easy applicability, the ddPCR technique is suitable for chimerism monitoring in clinical practice.

Keyphrases

stem cell transplantation
high dose
allogeneic hematopoietic stem cell transplantation
clinical practice
bone marrow
high throughput
single cell
acute lymphoblastic leukemia
big data
hematopoietic stem cell
artificial intelligence
deep learning