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Overexpression of lncRNA LINC00665 inhibits the proliferation and chondroblast differentiation of bone marrow mesenchymal stem cells by targeting miR-214-3p.

Siyuan ChenHui LiuYue WangShuyuan WangBo YangDi SunPengxiao Sun
Published in: Journal of orthopaedic surgery and research (2024)
Overexpression of lncRNA LINC00665 inhibited the proliferation and chondrogenic differentiation of BMSCs by targeting miR-214-3p. The LINC00665/miR-214-3p axis may improve joint damage and alleviate the progression of osteoarthritis.
Keyphrases
  • long non coding rna
  • long noncoding rna
  • bone marrow
  • cell proliferation
  • mesenchymal stem cells
  • signaling pathway
  • transcription factor
  • stem cells
  • oxidative stress
  • knee osteoarthritis