An In Vitro Circulatory Loop Model of the Pediatric Right Ventricular Outflow Tract as a Platform for Valve Evaluation.

Shannen B KizilskiXiaoya ZhangNicholas E KneierMartha D Chaillo LizarragaNoah E SchulzPeter E HammerDavid M Hoganson

Published in: Cardiovascular engineering and technology (2022)

The 3D-printed RVOT anatomical model and in vitro pulmonary circulatory loop developed in this work provide a platform for planning and evaluating surgical interventions in the pediatric population. Measurements of regurgitation, pressure gradient, and coaptation provide a quantitative basis for comparison among different valve designs and positions.

Keyphrases

aortic valve
aortic stenosis
mitral valve
high throughput
transcatheter aortic valve replacement
transcription factor
extracorporeal membrane oxygenation
physical activity
ejection fraction
coronary artery disease
atrial fibrillation
young adults