The Influence of Mediators on the Relationship Between Antenatal Opioid Agonist Exposure and the Severity of Neonatal Opioid Withdrawal Syndrome.
Lori A DevlinZhuopei HuSongthip OunpraseuthAlan E SimonRobert D AnnettAbhik DasJanell F FullerRosemary D HigginsStephanie L MerharP Brian SmithMargaret M CrawfordLesley E CottrellAdam J CzynskiSarah NewmanDavid A PaulPablo J SánchezErin O SemmensM Cody SmithBonny L WhalenJessica N SnowdenLeslie W Youngnull nullPublished in: Maternal and child health journal (2023)
MOUD exposure is directly associated with NOWS severity. Prenatal care and polysubstance exposure are potential mediators in this relationship. These mediating factors may be targeted to reduce the severity of NOWS while maintaining the important benefits of MOUD during pregnancy.