Sodium selenite attenuates lung adenocarcinoma progression by repressing SOX2-mediated stemness.

Weiwei ChenJiajia AnJiwei GuoYan WuLijuan YangJuanjuan DaiKaikai GongShuang MiaoSichuan XiJing Du

Published in: Cancer chemotherapy and pharmacology (2018)

Our results demonstrate that SS attenuates lung adenocarcinoma progression by repressing SOX2 and its upstream regulator GLI1, which suggests that SS may be a potential therapeutic drug candidate for lung cancer patients.

Keyphrases

transcription factor
stem cells
epithelial mesenchymal transition
emergency department
adverse drug