Targeted intraoperative radiotherapy tumour bed boost during breast-conserving surgery after neoadjuvant chemotherapy.
Hans-Christian KolbergGyoergy LoeveyLeyla Akpolat-BasciMiltiades StephanouPeter A FaschingMichael UntchCornelia LiedtkeMax BulsaraJayant S VaidyaPublished in: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] (2016)
IORT during lumpectomy after neoadjuvant chemotherapy as a tumour bed boost appears to give results that are not worse than external beam radiotherapy boost. These data give further support to the inclusion of such patients in the TARGIT-B (boost) randomised trial that is testing whether IORT boost is superior to EBRT boost.
Keyphrases
- neoadjuvant chemotherapy
- locally advanced
- lymph node
- sentinel lymph node
- rectal cancer
- squamous cell carcinoma
- radiation therapy
- early stage
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- cancer therapy
- radiation induced
- peritoneal dialysis
- big data
- study protocol
- artificial intelligence
- surgical site infection
- double blind