Visible-Light-Driven Decarboxylative Alkylation of C-H Bond Catalyzed by Dye-Sensitized Semiconductor.

A decarboxylative alkylation of benzylic C(sp3)-H bonds of N-aryl tetrahydroisoquinolines under the irradiation of blue light is reported, featuring a broad substrate scope, low cost, heavy-metal-free, and mild conditions. A preliminary mechanistic study indicated that radical intermediates are involved during the course of the reaction.