Diagnostic method-based underestimation of leptospirosis in clinical and research settings; an experience from a large prospective study in a high endemic setting.
Janith WarnasekaraLanka Acharige Shalka Madushan SrimanthaChamila KappagodaDinesha JayasundaraIndika SeneviratnaMichael A MatthiasSuneth Buddhika AgampodiJoseph M VinetzPublished in: PLoS neglected tropical diseases (2022)
Leptospirosis disease burden estimates should consider the limitations of standard diagnostic tests. qPCR of multiple sample types should be used as a leading standard test for diagnosing acute leptospirosis.