Exploring NK cell receptor dynamics in paediatric leukaemias: implications for immunotherapy and prognosis.

Cui TuIrina BuckleIngrid Leal RojasGustavo Rodrigues RossiDavid P SesterAndrew S MooreKristen J Radford Camille GuillereyFernando Souza-Fonseca-Guimaraes

Published in: Clinical & translational immunology (2024)

We provide an in-depth analysis of NK cell populations in paediatric leukaemia patients. These results support the development of immunotherapies targeting immunosuppressive receptors, such as NKG2A, to enhance innate immunity against paediatric leukaemia.

Keyphrases

nk cells
intensive care unit
emergency department
end stage renal disease
ejection fraction
chronic kidney disease
peritoneal dialysis
prognostic factors
cancer therapy
drug delivery