Noninvasive respiratory support following extubation in critically ill adults: a systematic review and network meta-analysis.

Shannon M FernandoAlexandre TranBehnam SadeghiradKaren E A BurnsEddy FanDaniel BrodieLaveena MunshiEwan C GoligherDeborah J CookRobert A FowlerMargaret S HerridgePierre CardinalSamir JaberMorten Hylander MøllerArnaud W ThilleNiall D FergusonArthur S SlutskyLaurent J BrochardAndrew J E SeelyBram Rochwerg

Published in: Intensive care medicine (2021)

Our findings suggest that both NIPPV and HFNC reduced reintubation in critically ill adults, compared to conventional oxygen therapy. NIPPV did not reduce incidence of reintubation when compared to HFNC. These findings support the preventative application of noninvasive respiratory support strategies to mitigate extubation failure in critically ill adults, but not in rescue conditions.

Keyphrases

cardiac surgery
mechanical ventilation
risk factors
stem cells
mesenchymal stem cells
respiratory failure
cell therapy
smoking cessation