The effects of certain TRP channels and voltage-gated KCNQ/Kv7 channel opener retigabine on calcitonin gene-related peptide release in the trigeminovascular system.

Arzu Citak Erkan Kilinc Ibrahim Ethem TorunSeyit AnkaraliYasar DagistanHamit Yoldas

Published in: Cephalalgia : an international journal of headache (2022)

Our findings suggest that favorable antagonists of these transient receptor potential channels, or Kv7 channel opener retigabine may be effective in migraine therapy by inhibiting neurogenic inflammation that requires calcitonin gene-related peptide release.

Keyphrases

genome wide
copy number
oxidative stress
spinal cord injury
genome wide identification
signaling pathway
image quality
magnetic resonance imaging
stem cells
computed tomography
transcription factor
risk assessment
dna methylation
binding protein
cerebral ischemia
replacement therapy
subarachnoid hemorrhage