Bioavailability and safety of diazepam intranasal solution compared to oral and rectal diazepam in healthy volunteers.

Robert Edward HoganBarry E GidalBarry KoplowitzLuana P KoplowitzRichard E LowenthalEnrique Carrazana

Published in: Epilepsia (2020)

Diazepam nasal spray shows predicable pharmacokinetics and represents a potential novel therapeutic approach to control bouts of increased seizure activity (cluster seizures, acute repetitive seizures).

Keyphrases

temporal lobe epilepsy
liver failure
high frequency
respiratory failure
drug induced
aortic dissection
hepatitis b virus
chronic rhinosinusitis
acute respiratory distress syndrome