Gestational diabetes mellitus is associated with distinct folate-related metabolites in early and mid-pregnancy: A prospective cohort study.
Wei ZhengYujie ZhangPuyang ZhangTengda ChenXin YanLin LiLijun ShaoZhiru SongWeiling HanJia WangJunhua HuangKaiwen MaRuihua YangYuru MaLili XuKexin ZhangXianxian YuanGuanghui LiPublished in: Diabetes/metabolism research and reviews (2024)
Elevated levels of UMFA and HCY during early pregnancy, along with elevated RBC 5-MTHF and 5,10-CH2-THF and plasma 5-MTHF during mid-pregnancy, are associated with GDM. These findings indicate distinct connections between different folate metabolites and the occurrence of GDM.