The impact of regional astrocyte interferon-γ signaling during chronic autoimmunity: a novel role for the immunoproteasome.

Brandon C SmithMaksim SinyukJulius E JenkinsMorgan W PsenickaJessica L Williams

Published in: Journal of neuroinflammation (2020)

Taken together, our data reveal a protective role for IFNγ in chronic neuroinflammation and identify a novel function of the iP in astrocytes during CNS autoimmunity.

Keyphrases

dendritic cells
immune response
traumatic brain injury
lipopolysaccharide induced
electronic health record
big data
celiac disease
single cell
machine learning
lps induced
cognitive impairment
inflammatory response
cerebral ischemia
artificial intelligence
subarachnoid hemorrhage