Outcomes of 23 patients diagnosed with New Delhi metallo-beta-lactamase (NDM)-producing Klebsiella pneumoniae infection treated with ceftazidime/avibactam and aztreonam at a single center in Poland.

Aneta Guzek Zbigniew Rybicki Dariusz Tomaszewski Katarzyna Mackiewicz Wiesław Piechota Andrzej Chciałowski

Published in: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology (2024)

The combination of CZA + AT is a safe and effective therapy for infections caused by KP-NDM, both at the clinical and microbiological levels. The synergistic action of all compounds resulted in a good agreement between the clinical efficacy of CZA + AT and the results of in vitro susceptibility testing.

Keyphrases

klebsiella pneumoniae
multidrug resistant
escherichia coli
gram negative
end stage renal disease
newly diagnosed
chronic kidney disease
ejection fraction
prognostic factors
type diabetes
insulin resistance
patient reported outcomes