Deep palmar phenotyping in atopic eczema: patterns associated with Filaggrin variants, disease severity and barrier function in a South Asian population.

Bjorn R ThomasXiang Li TanStefan Van DuijvenbodenSarah C HoganAaron J HughesSoha S TawfikSasha DhoatRavinder AtkarElizabeth J RobinsonSyedia R RahmanSamiha RahmanRehana A AhmedRubina BegumHabiba KhanamEmma L BourneEva L WozniakCharles A MeinDavid P KelsellEdel A O'Toole

Published in: The British journal of dermatology (2023)

Palm patterns associate with EASI and TEWL. The fine perpendicular/prominent diamond patterns are markers to detect absence/presence of LoF FLG variants respectively.

Keyphrases

atopic dermatitis
copy number
air pollution
gene expression
dna methylation
genome wide
single cell