Spin-lock relaxation rate dispersion reveals spatiotemporal changes associated with tubulointerstitial fibrosis in murine kidney.

Feng WangDaniel C ColvinSuwan WangHua LiZhongliang ZuRaymond C HarrisMing-Zhi ZhangJohn C Gore

Published in: Magnetic resonance in medicine (2020)

Both Sρ and ωinfl depend primarily on the average exchange rate between water and other chemically shifted resonances such as hydroxyls and amides. Spin-lock relaxation rate dispersion, rather than single measurements of relaxation rates, provides more comprehensive and specific information on spatiotemporal changes associated with tubulointerstitial fibrosis in murine kidney.

Keyphrases

single molecule
room temperature
density functional theory
healthcare
liver fibrosis
molecular dynamics