Bioinformatic analysis identifies key transcriptome signatures in temporal lobe epilepsy.

Qing-Lan ChenLu XiaShao-Ping ZhongQiang WangJing DingXin Wang

Published in: CNS neuroscience & therapeutics (2020)

Our integrated analysis identified hub genes in different stages of epilepsy. The functional annotations suggest that the activation and phagocytic activities of microglia/macrophages may play critical roles in epileptogenesis of TLE.

Keyphrases

genome wide
temporal lobe epilepsy
gene expression
inflammatory response
spinal cord injury
rna seq
neuropathic pain
data analysis
genome wide analysis